CoLumbo is software for analysis of Lumbar spine images obtained with MRI.

CoLumbo is software for analysis of lumbar spine images obtained with MRI. The purpose of CoLumbo is to assist with the reading of MRI images on the lumbar spine and to provide information on suspected pathologies and abnormality detection, and reduce the time to record the readings. According to the Spine Reporting Survey we conducted, the radiologists think that on average about 17.2 minutes are needed for thorough L-Spine MRI examination in cases without any complications and about 30 minutes for more complex cases, but they have only 13.6 minutes on average for MRI reading in a real clinical situation at the cost of up to 30% errors and omissions.

The key novelty of CoLumbo lies in the unique machine learning algorithm, based on fully convolutional neural networks combined with medical domain knowledge, dropout regularization, and packet normalization which are capable of reading MRI images, to assist qualified clinicians in providing a complete diagnosis. U-Net-like architecture is used to improve the resolution.

The first step is the Segmentation of specific structures which is made on a pixel level and the use of fully convolutional neural networks allows quick segmentation maps to be generated for images of any size. The second is the identification of key points in the MRI images. After this is the measurement of distances, areas and angles. Finally, the combination of segmentation, measurements, and specially applied algorithms provides the qualified clinicians with an asisstance in complete diagnosis according to the parameters described in the scientific medical literature. All findings are presented in a easy-to-use final draft report, which is currently available in English, Bulgarian, German, French, Spanish, Italian, Romanian, Polish and Dutch.  More languages will be added soon.

The main benefits of CoLumbo are lower cost, ease of use and optimal cost-result ratio. CoLumbo holds the potential to alleviate the economic burden imposed on the business as the low cost of the service will render it available to a bigger part of the population, thus helping with the implementation of preventative measures which will lower the number of chronically disabled employees.

Another key benefit of CoLumbo is the possibility to completely customize all thresholds and ranges of the findings. For example, for herniation, one can report the severity in two or three levels and modify the minimum threshold size for each level, indicated in millimeters. Additional fine-tuning settings are available, such as herniation zone reporting, cranial or caudal migration reporting, and dural sac compression reporting. These settings are available for all pathologies covered.

FEATURES OF COLUMBO

RELATED PATHOLOGIES AND OTHER FINDINGS:

  • HERNIATION AND ITS SIZE, LOCATION AND POSSIBLE DESCENDING AND/OR ASCENDING MIGRATION
  • PROTRUSION AND EXTRUSION HERNIATION MODIFIERS
  • NERVE ROOT IMPINGEMENT
  • DURAL SAC COMPRESSION
  • CENTRAL SPINAL STENOSIS – SCHIZAS AND LEE MORPHOLOGICAL GRAIDNG
  • ANTERO AND RETRO – SPONDYLOLISTHESIS
  • SYMMETRICAL AND ASYMMETRICAL BULGING
  • HYPO AND HYPER-LORDOSIS
  • REDUCED DISK HEIGHT
  • REDUCED VERTEBRAL BODY HEIGHT
  • AXIAL FORAMINAL SIZE
  • OSTEOPHITES
  • FAT INFILTRATION IN MUSCLE TISSUE
  • LIPOMATHOSIS
  • LATERAL RECESS STENOSIS

TISSUE BOUNDARIES:

  • LEVEL LABELS
  • VERTEBRAL BODY
  • OTHER PARTS OF THE VERTEBRA
  • DISC
  • HERNIATED PART OF THE DISK
  • DURAL SAC
  • NERVE ROOTS
  • LIGAMENTUM FLAVUM

MEASUREMENTS PERFORMED:

  • SIZE OF HERNIATION
  • HERNIATION CIRCUMFERENCE
  • HERNIATION LOCATION SCORE
  • PROTRUSION AP SIZE
  • EXTRUSION AP, CC, LR SIZE
  • MIGRATION SIZE
  • NERVE ROOT IMPINGEMENT SCORE
  • DURAL SAC AREA AND STENOTIC RATIO
  • SPINAL CANAL AP DIAMETER
  • LISTHESIS PERCENTAGE AND GRADE
  • L1S1, L1L5 AND L1L4 LORDOTIC ANGLES
  • BULGING SIZE
  • BULGING CIRCUMFERENCE
  • BULGING SYMMETRY SCORE
  • DISC HEIGHT (ANTERIOR, MIDDLE, POSTERIOR) AND RATIOS
  • VERTEBRAL BODY HEIGHT (ANTERIOR, MIDDLE, POSTERIOR)
  • INTERVERTEBRAL ANGLES
  • FACET JOINT THICKNESS SIZE
  • FACE JOINT ANGLE
  • PSEUDOLISTHESIS SLIPPAGE
  • FORAMINAL STENOSIS CLEARANCE SIZE DURAL SAC BRIGHTNESS AND CONTRAST COEFFICIEN

REPORT LANGUAGES:

  • ENGLISH
  • BULGARIAN
  • FRENCH
  • DUTCH
  • SPANISH
  • ITALIAN
  • GERMAN
  • ROMANIAN
  • POLISH